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Document ID (ISN)64281
CIS number 95-648
ISSN - Serial title 0003-4878 - Annals of Occupational Hygiene
Year 1994
Convention or series no.
Author(s) VanRooij J.G.M., Bodelier-Bade M.M., Hopmans P.M.J., Jongeneelen F.J.
Title Reduction of urinary 1-hydroxypyrene excretion in coke-oven workers exposed to polycyclic aromatic hydrocarbons due to improved hygienic skin protective measures
Bibliographic information June 1994, Vol.38, No.3, p.247-256. Illus. 19 ref.
Abstract The effect of hygienic skin protective measures on the internal exposure to polycyclic aromatic hydrocarbons (PAHs) was studied in 13 coke-oven workers over two consecutive weeks. In one week the subjects worked under normal circumstances, in the other extra hygienic skin protective measures were taken: laundered working clothes and a new pair of gloves were provided before each 8h work shift, and both hands and face were washed before each break. The effect of the extra hygienic measures on the urinary 1-hydroxypyrene excretion which indicates internal PAH exposure was assessed by biological monitoring. Urinary 1-hydroxypyrene concentration over the four-day work week was on average 37% lower when extra hygienic measures were taken, being 1.3 instead of 2.3Ámole 1-hydroxypyrene per mole creatinine (p=0.03, n=13). Thus, simple hygienic skin protective measures resulted in a significant reduction of the internal PAH exposure.
Descriptors (primary) metabolic process; pyrene; aromatic hydrocarbons; skin protection; coke ovens; personal hygiene; polycyclic hydrocarbons; urinary excretion
Descriptors (secondary) protective gloves; comparative study; exposure evaluation; protective clothing
Document type D - Periodical articles
Country / State or ProvinceNetherlands
Subject(s) Metal production and metalworking
Broad subject area(s) Chemical safety
Browse category(ies) Aromatic hydrocarbons
Skin protection
Polycyclic hydrocarbons