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CISDOC database
| Document ID (ISN) | 64087 |
| CIS number |
95-668 |
| Year |
1994 |
| Convention or series no. |
ECETOC JACC No.25
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| Title |
1-Chloro-1,2,2,2-tetrafluoroethane (HCFC 124) CAS No.2837-89-0 |
| Bibliographic information |
European Centre for Ecotoxicology and Toxicology of Chemicals, Avenue E. Van Nieuwenhuyse 4, Bte.6, 1160 Bruxelles, Belgium, July 1994. ii, 23p. 38 ref. |
| Abstract |
1-Chloro-1,2,2,2-tetrafluoroethane is a non-flammable colourless gas that is currently under development as a chlorofluorocarbon alternative and is not yet available commercially. It has a low order of acute inhalation toxicity (the 4h LC50 in rats is between 1,283,400 and 1,674,000mg/m3 = 230,000 and 300,000ppm). The main toxicological action is weak anaesthesia. Cardiac sensitization in dogs is observed above 26,000ppm. No mutagenicity or developmental toxicity has been observed in laboratory experiments. No effects on human beings have been reported. An occupational exposure limit (8h time-weighted average) of 1000ppm is recommended by producers. |
| Descriptors (primary) |
threshold limit values; 1-chloro-1,2,2,2-tetrafluoroethane; toxicology; chemical industry |
| Descriptors (secondary) |
toxic effects; criteria document; literature survey |
| Document type |
E - Books, reports, proceedings |
| Country / State or Province | Belgium |
| Subject(s) |
Toxic and dangerous substances
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| Broad subject area(s) |
Chemical safety
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| Browse category(ies) |
Chemical industry
Occupational exposure limits
Halogenated hydrocarbons
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