Document ID (ISN) | 63969 |
CIS number |
95-632 |
ISSN - Serial title |
0007-5914 - Bundesgesundheitsblatt |
Year |
1994 |
Convention or series no. |
|
Author(s) |
Appel K.E. |
Title |
On the carcinogenicity of pentachlorophenol |
Original title |
Zur kanzerogenen Wirkung von Pentachlorphenol [in German] |
Bibliographic information |
Aug. 1994, Vol.37, No.8, p.334-341. 61 ref. |
Abstract |
Pentachlorophenol (PCP) has been widely used in industry, agriculture, and in homes as a pesticide and herbicide. It finds its widest use in wood impregnation. Data on the carcinogenicity of PCP are reviewed. The substance is carcinogenic in B6C3F1-mice. In addition, there is evidence that some metabolites of PCP are genotoxic. Epidemiologic studies have not provided proof or disproof of a carcinogenic effect in humans. The present exposure limit of 1µg/m3 air recommended by the German Bureau of Health is on the safe side on the basis of present knowledge. |
Descriptors (primary) |
carcinogens; carcinogenic effects; hazard evaluation; pentachlorophenol |
Descriptors (secondary) |
herbicides; literature survey; dangerous substances; Germany; pesticides; agriculture; permissible levels; epidemiologic study; animal experiments; genetic effects; wood impregnation |
Document type |
D - Periodical articles |
Country / State or Province | Germany |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Risk evaluation Phenols and phenolic compounds Alcohols Genetic factors in reaction to exposures
|