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Document ID (ISN)63463
CIS number 94-1978
ISSN - Serial title 0002-8894 - American Industrial Hygiene Association Journal
Year 1994
Convention or series no.
Author(s) Woskie S.R., Smith T.J., Hallock M.F., Hammond S.K., Rosenthal F., Eisen E.A., Kriebel D., Greaves I.A.
Title Size-selective pulmonary dose indices for metal-working fluid aerosols in machining and grinding operations in the automobile manufacturing industry
Bibliographic information Jan. 1994, Vol.55, No.1, p.20-29. Illus. 32 ref.
Abstract The current metal-working fluid exposures at three locations that manufacture automotive parts were assessed in conjunction with epidemiological studies of the mortality and respiratory morbidity of workers at these plants. Comparison of the results obtained from personal impactor samples with predictions from an aerosol-deposition model for the human respiratory tract showed high correlation. However, the amount collected on the impactor stage underestimates extrathoracic deposition and overestimates tracheobronchial and alveolar deposition, as calculated by the deposition model. The rank order of cumulative thoracic concentration over subjects' working lives was the same when based on the deposition model as on the basis of the impactor concentrations. However, the cumulative impactor concentration values were significantly higher than the cumulative deposition-model concentration values for the subjects.
Descriptors (primary) lung deposition; abrasive operations; aerosols; dose-response relationship; exposure evaluation; motor vehicle industry; cutting fluids
Descriptors (secondary) mathematical models
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Motor vehicle manufacturing industry
Exposure evaluation