| Document ID (ISN) | 63463 |
| CIS number |
94-1978 |
| ISSN - Serial title |
0002-8894 - American Industrial Hygiene Association Journal |
| Year |
1994 |
| Convention or series no. |
|
| Author(s) |
Woskie S.R., Smith T.J., Hallock M.F., Hammond S.K., Rosenthal F., Eisen E.A., Kriebel D., Greaves I.A. |
| Title |
Size-selective pulmonary dose indices for metal-working fluid aerosols in machining and grinding operations in the automobile manufacturing industry |
| Bibliographic information |
Jan. 1994, Vol.55, No.1, p.20-29. Illus. 32 ref. |
| Abstract |
The current metal-working fluid exposures at three locations that manufacture automotive parts were assessed in conjunction with epidemiological studies of the mortality and respiratory morbidity of workers at these plants. Comparison of the results obtained from personal impactor samples with predictions from an aerosol-deposition model for the human respiratory tract showed high correlation. However, the amount collected on the impactor stage underestimates extrathoracic deposition and overestimates tracheobronchial and alveolar deposition, as calculated by the deposition model. The rank order of cumulative thoracic concentration over subjects' working lives was the same when based on the deposition model as on the basis of the impactor concentrations. However, the cumulative impactor concentration values were significantly higher than the cumulative deposition-model concentration values for the subjects. |
| Descriptors (primary) |
lung deposition; abrasive operations; aerosols; dose-response relationship; exposure evaluation; motor vehicle industry; cutting fluids |
| Descriptors (secondary) |
mathematical models |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Exposure evaluation
Motor vehicle manufacturing industry
|
