Document ID (ISN) | 63412 |
CIS number |
94-2027 |
ISBN(s) |
3-7776-0574-3 |
Year |
1994 |
Convention or series no. |
BUA Report 58
|
Author(s) |
Gesellschaft Deutscher Chemiker (GDCh) - Advisory Committee on Existing Chemicals of Environmental Relevance (BUA) |
Title |
Butylated hydroxytoluene (2,6-bis(1,1-dimethylethyl)-4-methylphenol) |
Bibliographic information |
S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1994. xv, 116p. 197 ref. |
Abstract |
Only a few studies are available on the sensitizing effects of butylated hydroxytoluene (2,6-di-tert-butyl-p-cresol) in humans. In one study it is described as mildly irritating to the skin and moderately sensitizing in human patch tests; contact dermatitis and allergic reactions have also been reported. Animal studies indicate that the substance affects the lungs, liver, kidneys and thyroid gland; contradictory results are available on carcinogenicity, mutagenicity and reproduction disturbances. |
Descriptors (primary) |
2,6-di-tert-butyl-p-cresol; ecotoxicology; toxicology; Germany |
Descriptors (secondary) |
toxic effects; literature survey; irritants; eczema; allergic reactivity; animal experiments; comment on law; comment on directive; criteria document; sensitizers |
Document type |
E - Books, reports, proceedings |
Country / State or Province | Germany |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
Chemical safety
|
Browse category(ies) |
Pollution control Alcohols
|