| Document ID (ISN) | 63362 |
| CIS number |
94-1989 |
| ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
| Year |
1994 |
| Convention or series no. |
|
| Author(s) |
Crump K.S. |
| Title |
Risk of benzene-induced leukemia: A sensitivity analysis of the Pliofilm cohort with additional follow-up and new exposure estimates |
| Bibliographic information |
June 1994, Vol.42, No.2, p.219-242. 34 ref. |
| Abstract |
This reports updates an earlier risk assessment for benzene-induced leukaemia which was used by OSHA in the establishment of permissible exposure limits. The present study was based on mortality data on a cohort of workers employed at two Pliofilm manufacturing plants where there were relatively high exposures to benzene. New risk estimates are derived using follow-up data to 1987 and using new exposure estimates. Results indicate a significant excess of acute myelocytic or acute monocytic leukaemia and a strong dose-response trend. |
| Descriptors (primary) |
leukaemia; hazard evaluation; benzene |
| Descriptors (secondary) |
mortality; mathematical models; cohort study; exposure evaluation |
| Document type |
D - Periodical articles |
| Country / State or Province | USA |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Aromatic hydrocarbons
Risk evaluation
Leukaemia
|
