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Document ID (ISN)62969
CIS number 94-1639
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1991
Convention or series no.
Author(s) Vyskocil A., Popler A., Skutilova I., Ciharova M., Ettlerova E., Lauwerys R.R., Bernard A.M.
Title Urinary excretion of proteins and enzymes in workers exposed to hydrocarbons in a shoe factory
Bibliographic information 1991, Vol.63, No.5, p.359-362. Illus. 18 ref.
Abstract A study was made of a group of women who had been exposed to petroleum naphtha (time-weighted average exposure 1,619mg/m3), toluene 81mg/m3) and ethylacetate (160mg/m3). Measurements were made of urinary enzyme activity and proteins and compared with those of age-matched controls. The only parameter that was significantly influenced by hydrocarbon exposure was the urinary activity of beta-N-acetylglucosaminidase. Although the health significance of this renal change in unclear, the results are in agreement with previous observations suggesting that long-term moderate exposure to solvents does not entail a significant risk for the development of nephrotoxicity.
Descriptors (primary) ethyl acetate; toluene; shoe industry; urinary metabolites; naphtha
Descriptors (secondary) proteins; enzyme activity; determination in urine; nephrotoxic effects; proteinuria
Document type D - Periodical articles
Country / State or ProvinceBelgium; Czechoslovakia
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Footwear, leather and fur industry
Aromatic hydrocarbons
Esters and salts