| Document ID (ISN) | 62576 |
| CIS number |
94-1229 |
| ISSN - Serial title |
0003-0805 - American Review of Respiratory Disease |
| Year |
1993 |
| Convention or series no. |
|
| Author(s) |
Lalancette M., Carrier G., Laviolette M., Ferland S., Rodrique J., Bégin R., Cantin A., Cormier Y. |
| Title |
Farmer's lung - Long-term outcome and lack of predictive value of bronchoalveolar lavage fibrosing factors |
| Bibliographic information |
July 1993, Vol.148, No.1, p.216-221. Illus. 32 ref. |
| Abstract |
This study evaluates the long-term outcome of farmer's lung (FL), adding high-resolution computed tomograms (HRCT) to previously reported procedures and verifying whether bronchoalveolar lavage (BAL) fluid markers or fibrogenic factors (FF) predict outcome. Pulmonary function tests on FL subjects revealed an obstructive profile in 13 subjects and normal values in 16. Chest radiographs (CXR) were normal in 22 subjects, abnormal in six, and suggestive of emphysema in five. HRCT revealed emphysema in nine subjects and 19 were normal. There was a good correlation between the findings on pulmonary function tests and HRCT; however, CXR alone did not suggest the existence of emphysema in four subjects who had such findings on HRCT. No correlations were found between most outcome parameters and the level of the BAL FF measured six years previously. Airflow obstruction with or without emphysema is an important long-term sequela of FL and BAL FF do not predict outcome in this disease. |
| Descriptors (primary) |
farmer's lung; bronchopulmonary lavage; assessment of fibrogenicity; fibrogenic effects |
| Descriptors (secondary) |
obstructive ventilatory impairment; emphysema; diagnosis; tomography; prediction; respiratory impairment; chest radiography; respiratory function tests |
| Document type |
D - Periodical articles |
| Country / State or Province | Canada |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Occupational medicine, epidemiology
|
| Browse category(ies) |
Pneumoconioses
|
