|Document ID (ISN)||62486|
|ISSN - Serial title
||0342-0809 - Kompass
|Convention or series no.
||Potthast J., Marek W., Marczynski B., Baur X.
||Isocyanates on the workplace - Diseases of the respiratory tract and the lung
||Isocyanate am Arbeitsplatz - Erkrankungen der Atemwege und der Lunge [in German]|
||July 1993, Vol.103, No.7, p.338-345. Illus. 33 ref.
||The results of experimental studies of the effects of isocyanates such as diphenylmethane diisocyanate (MDI), tolylene diisocyanate (TDI) and hexamethylene diisocyanate (HDI) over a two-year period are summarized. In vivo short-term exposure to 10ppb TDI led to bronchial hypersensitivity. In vivo and in vitro exposure to the isocyanates produced breaks in DNA. A reduction of the present maximum workplace concentration for TDI is recommended.
||diphenylmethane diisocyanate; hexamethylene diisocyanate; tolylene diisocyanate; construction industry; motor vehicle industry; allergic reactivity; furniture industry; respiratory impairment; anthracite mining; allergic respiratory disorders; hypersensitivity
||allergens; obstructive ventilatory impairment; in vitro experiments; experimental pathology; isocyanates
||D - Periodical articles
|Country / State or Province||Germany|
|Broad subject area(s)
||Diseases of the respiratory system (except for pneumoconiosis & similar)
Lumber and the woodworking industry
Motor vehicle manufacturing industry
Construction industry and civil engineering
Mining and quarrying