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CISDOC database

Document ID (ISN)62401
CIS number 94-1008
ISBN(s) 3-7776-0548-4
Year 1993
Convention or series no. BUA Report 56
Author(s)
Gesellschaft Deutscher Chemiker (GDCh) Advisory Committee on Existing Chemicals of Environmental Relevance (BUA)
Title Morpholine
Bibliographic information S. Hirzel Verlag, P.O. Box 10 10 61, 70009 Stuttgart, Germany, 1993. xx, 152p. 266 ref. Price: DEM 88.00.
Abstract Limited data are available on the toxic effects of morpholine in humans. The substance has an unpleasant fishy odour with an odour threshold of 0.036mg/m3. Experiments on human volunteers indicate that it may cause irritation of the eyes, nose and throat and skin burns. Animal studies show that the target organs are the liver, kidneys an stomach. There are no indications that morpholine itself is carcinogenic, although in the presence of nitrite it may be converted to N-nitrosomorpholine which is known to be mutagenic and carcinogenic in animals.
Descriptors (primary) Germany; ecotoxicology; toxicology; morpholine
Descriptors (secondary) toxic effects; literature survey; irritants; criteria document; odour threshold; animal experiments; legislation; caustic substances
Document type E - Books, reports, proceedings
Country / State or ProvinceGermany
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Pollution control
Heterocyclic compounds