ILO Home
Go to the home page
Site map | Contact us Français | Espańol

CISDOC database

Document ID (ISN)61673
CIS number 94-318
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1993
Convention or series no.
Author(s) Štětkářová I., Urban P., Procházka B., Lukáš E.
Title Somatosensory evoked potentials in workers exposed to toluene and styrene
Bibliographic information June 1993, Vol.50, No.6, p.520-527. Illus. 47 ref.
Abstract Somatosensory evoked potentials (SEPs) were used to evaluate possible subclinical impairment of the nervous system in 36 rotogravure printers with severe exposure to toluene, 20 workers with severe exposure to styrene in a glass laminate manufacturing plant, and a comparison group of healthy subjects. Exposure was estimated by measurements of toluene and styrene in breathing zone air, hippuric acid in urine in the group exposed to toluene, and urinary mandelic acid in the group exposed to styrene. Peripheral conduction velocities in the arm and leg, and central conduction time after tibial nerve stimulation were decreased in both exposed groups. Prolonged latencies of peripheral and cortical SEPs were found in workers exposed to styrene. Some abnormalities in SEP's at peripheral or spinal and cortical levels were found in both groups. A trend toward increased frequency of abnormal SEPs with duration of exposure of toluene and styrene and alcohol abuse was found. Abnormalities in SEPs in the exposed groups are most probably of multifactorial origin. Central SEP abnormalities in both exposed groups could indicate early signs of subclinical dysfunction at spinal and cortical levels and could be due to toluene or styrene exposure, probably potentiated by alcohol consumption in the group exposed to toluene.
Descriptors (primary) toluene; styrene; diseases of nervous system; photogravure printing; glass industry; sensorimotor activities; nerve stimulation tests
Descriptors (secondary) nervous function tests; functional nervous disorders; determination in urine; determination in air; cohort study
Document type D - Periodical articles
Country / State or ProvinceCzech Republic
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Glass, pottery and related materials
Aromatic hydrocarbons
Printing, photography and photocopying industry