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Document ID (ISN)59852
CIS number 93-491
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1992
Convention or series no.
Author(s) Eriksson M., Hardell L., Malker H., Weiner J.
Title Malignant lymphoproliferative diseases in occupations with potential exposure to phenoxyacetic acids or dioxins - A register-based study
Bibliographic information Sep. 1992, Vol.22, No.3, p.305-312. 23 ref.
Abstract The Swedish Cancer Environment Register (CER) is a linkage of census data (e.g. on occupations) with the Swedish Cancer Register. It has been used in different studies to generate hypotheses on occupational risk factors for malignant tumours. This study investigates the risk for malignant lymphoma and multiple myeloma in occupations with potential exposure to phenoxyacetic acids or other related substances. An increased standardised incidence ratio (SIR) of 1.3 for multiple myeloma was verified in farmers (335 cases). For malignant lymphoma, an increased SIR of 1.2 was found in farmers (227 cases). Non-Hodgkin's lymphoma studied separately showed an increased risk (SIR=1.2) in carpenters only (149 cases), whereas Hodgkin's disease had an increased SIR of 2.1 in sawmill workers (10 cases). Physicians also had an elevated risk for malignant lymphoma. A major shortcoming in register studies such as CER is that no individual exposure data on different agents are available. The lack of an association between an occupation and a specific malignant disease may not, therefore, be taken as evidence that persons within that occupation are not at an increased risk for that disease.
Descriptors (primary) phenoxyacetic acids; dioxins; lymphoma; Hodgkin's disease; sawmilling industry; occupation disease relation; myeloma; exposure evaluation; agriculture; morbidity
Descriptors (secondary) Sweden; toxic substances; neoplasms; registers of occupational diseases; risk factors
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Blood diseases
Exposure evaluation
Heterocyclic compounds
Lumber and the woodworking industry
Woodworking industry
Agriculture