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CISDOC database

Document ID (ISN)59643
CIS number 93-141
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 1991
Convention or series no.
Author(s) Merletti F., Vineis P., Bertazzi P.A.
Title Problems and prospects in occupational carcinogenesis
Original title Problemi e prospettive nella cancerogenesi occupazionale [in Italian]
Bibliographic information July-Aug. 1991, Vol.82, No.4, p.314-327. 56 ref.
Abstract Epidemiological research has played an important role in identifying and confirming the carcinogenicity of chemicals. This was facilitated in the past by high levels of exposure and by the simple correspondence between one kind of exposure and one or few job titles. Today we are faced with a different picture: workers are exposed to complex mixtures, exposure levels have decreased while mobility of the workforce has increased. In this changing context, epidemiology needs new methodological tools to improve the validity of risk assessment. The most promising of these seem to be the new techniques of biochemical epidemiology and the development of job-exposure matrices. Among the more traditional tools, record-linkage studies may be relevant in identifying long-term occupational hazards. The methodological problems and the ethical and operative implications of these trends in research are discussed.
Descriptors (primary) carcinogens; carcinogenic effects; epidemiology
Descriptors (secondary) literature survey; research; list of chemical substances
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Epidemiology
Ethical issues