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Document ID (ISN)59132
CIS number 92-1979
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1992
Convention or series no.
Author(s) Leira H.L., Tiltnes A., Svendsen K., Vetlesen L.
Title Irritant cutaneous reactions to N-methyl-2-pyrrolidone (NMP)
Bibliographic information Sep. 1992, Vol.27, No.3, p.148-150. 9 ref.
Abstract Several workers in a small electrotechnical company in Norway experienced irritant reactions of the skin after a few days of working with the solvent N-methyl-2-pyrrolidone (NMP). Due to concern about the health risk of commonly-used organic solvents, the company had chosen to use NMP when one of its products had to be treated with a solvent. After 2 days of work with NMP, 10 of the 12 involved workers displayed acute irritant contact dermatitis of the hands. According to published reports, NMP is not considered to be particularly irritant to the skin. The Safety Data Sheet of a Norwegian sales firm contained no information on cutaneous hazards, but the Safety Data Sheet of an American producer of NMP stated the risk of severe dermatitis upon prolonged contact. NMP seems to be more irritant to the human skin than reported thus far.
Descriptors (primary) skin diseases; eczema; methylpyrrolidinone; exposure evaluation; electronics industry; organic solvents
Descriptors (secondary) protective gloves; toxic substances; irritation
Document type D - Periodical articles
Country / State or ProvinceNorway
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Manufacturing of electrical appliances and equipment
Electronics industry
Exposure evaluation
Skin diseases
Heterocyclic compounds