ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)58979
CIS number 92-1877
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1992
Convention or series no.
Author(s) Riihimńki V., Kivist÷ H., Peltonen K., Helpi÷ E., Aitio A.
Title Assessment of exposure to carbon disulfide in viscose production workers from urinary 2-thiothiazolidine-4-carboxylic acid determinations
Bibliographic information July 1992, Vol.22, No.1, p.85-97. Illus. 19 ref.
Abstract The follow-up of environmental carbon disulfide (CS2) exposure and urinary excretion of 2-thiothiazolidine-4-carboxylic acid (TTCA) among 20 operatives over a four-day working week in two viscose producing factories confirmed earlier observations that TTCA is a sensitive and reliable indicator of exposure to CS2. Exposure to as low as 0.5-1.0ppm (1.6-3.2mg/m3) of CS2 was associated with detectable amounts of TTCA in urine. Approximately 3% (range 2-6.5%) of absorbed CS2 was detected in urine as TTCA. Consequently, urinary excretion of TTCA, relative to CS2 exposure, increased by about one-third during the working week. Urinary TTCA concentration of 4.5mmol/mol creatinine in a postshift sample corresponded to a TWA exposure to 10ppm CS2 towards the end of the working week.
Descriptors (primary) viscose rayon industry; carbon disulfide; determination in urine; exposure tests; 2-thiothiazolidine-4-carboxylic acid
Descriptors (secondary)
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Toxic and dangerous substances
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Biological monitoring
Inorganic sulfur compounds
Heterocyclic compounds
Inorganic substances