|Document ID (ISN)||58802|
|ISSN - Serial title
||0007-1072 - British Journal of Industrial Medicine
|Convention or series no.
||Ruijten M.W.M.M., Verberk M.M., SallÚ H.J.A.
||Nerve function in workers with long term exposure to trichloroethene
||Feb. 1991, Vol.48, No.2, p.87-92. Illus. 19 ref.
||Certain functions of the nervous system were compared between 31 printing workers (mean age 44) exposed to trichloroethene (trichloroethylene) (mean duration 16 years) and 28 controls (mean age 45). The mean cumulative exposure of the exposed workers was 704ppm x years. For the assessment of the exposure effect relation a multiple linear regression model was used. In the sural nerve the conduction velocity was reduced and the refractory period was prolonged. The latency of masseter, but not of the blink reflex, was increased. No impairment was found in the functions of motor and autonomic nerves. Thus, refractory period may be a sensitive indicator of preclinical toxic neuropathies. Long-term exposure to trichloroethene at threshold limit values (about 35ppm) may slightly affect the trigeminal and sural nerves.
||neurotoxic effects; long-term exposure; trichloroethylene; printing industry
||nervous function tests; cumulative properties; heart rate monitoring; conduction velocity
||D - Periodical articles
|Country / State or Province||Netherlands|
||Toxic and dangerous substances
|Broad subject area(s)
||Printing, photography and photocopying industry
Diseases of the nervous system