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CISDOC database

Document ID (ISN)58415
CIS number 92-1256
ISSN - Serial title 0007-1072 - British Journal of Industrial Medicine
Year 1991
Convention or series no.
Author(s) Stňhlbom B., Lundh T., FlorÚn I., ┼kesson B.
Title Visual disturbances in man as a result of experimental and occupational exposure to dimethylethylamine
Bibliographic information Jan. 1991, Vol.48, No.1, p.26-29. Illus. 16 ref.
Abstract Experimental exposure of four volunteers to 40-50mg/m3 of dimethylethylamine (DMEA) for eight hours caused irritation of the mucous membrane of their eyes, subjective visual disturbances (haze) and slight oedema of the corneal epithelium. The thickness of the cornea showed a slight but consistent increase in all four subjects at these exposures and in two subjects exposed to 10mg/m3. Concentrations of 80 and 160mg/m3 for 15 minutes caused eye irritation but no visual disturbances or corneal oedema. Occupational exposure for eight hours to about 25mg/m3 of DMEA (with peaks above 100mg/m3) was also associated with eye irritation, haze, and corneal oedema. The divergence between our findings and other reports in which visual disturbances occurred at low concentrations during occupational exposure may be due to peak concentrations.
Descriptors (primary) diseases of eyes and related structures; ophthalmotoxic effects; ethyldimethylamine
Descriptors (secondary) threshold limit values; experimental determination; human experiments; visual function disorders
Document type D - Periodical articles
Country / State or ProvinceSweden
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Aliphatic amines
Diseases of the eye and vision damage