| Document ID (ISN) | 58306 |
| CIS number |
92-1249 |
| ISSN - Serial title |
0105-1873 - Contact Dermatitis |
| Year |
1992 |
| Convention or series no. |
|
| Author(s) |
Stubb S., Heikkilä H., Reitamo S., Förström L. |
| Title |
Contact allergy to tioconazole |
| Bibliographic information |
Mar. 1992, Vol.26, No.3, p.155-158. 3 ref. |
| Abstract |
In 15 months, allergic patch test reactions to tioconazole in 14 patients were detected; 9 of the 14 patients were allergic to additional imidazole derivatives used as antifungal agents. The positive patch test reactions to tioconazole may have been caused either by simultaneous sensitisation or more probably by cross-reactivity between the various commercially used imidazole derivatives with a similar chemical structure. The abundant use of tioconazole in concentrated (up to 28%) topical formulations in Finland could be the major cause of the apparent increase in allergic reactions. |
| Descriptors (primary) |
imidazoles; skin tests; eczema |
| Descriptors (secondary) |
skin allergies; Finland |
| Document type |
D - Periodical articles |
| Country / State or Province | Finland |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Skin diseases
Heterocyclic compounds
|
