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Document ID (ISN)58306
CIS number 92-1249
ISSN - Serial title 0105-1873 - Contact Dermatitis
Year 1992
Convention or series no.
Author(s) Stubb S., Heikkilä H., Reitamo S., Förström L.
Title Contact allergy to tioconazole
Bibliographic information Mar. 1992, Vol.26, No.3, p.155-158. 3 ref.
Abstract In 15 months, allergic patch test reactions to tioconazole in 14 patients were detected; 9 of the 14 patients were allergic to additional imidazole derivatives used as antifungal agents. The positive patch test reactions to tioconazole may have been caused either by simultaneous sensitisation or more probably by cross-reactivity between the various commercially used imidazole derivatives with a similar chemical structure. The abundant use of tioconazole in concentrated (up to 28%) topical formulations in Finland could be the major cause of the apparent increase in allergic reactions.
Descriptors (primary) imidazoles; skin tests; eczema
Descriptors (secondary) skin allergies; Finland
Document type D - Periodical articles
Country / State or ProvinceFinland
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Skin diseases
Heterocyclic compounds