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CISDOC database

Document ID (ISN)57361
CIS number 92-195
ISSN - Serial title 0096-1736 - Journal of Occupational Medicine
Year 1991
Convention or series no.
Author(s) Gobba F., Galassi C., Imbriani M., Ghittori S., Candela S., Cavalleri A.
Title Acquired dyschromatopsia among styrene-exposed workers
Bibliographic information July 1991, Vol.33, No.7, p.761-765. Illus. 24 ref.
Abstract The occurrence of colour vision loss in 75 styrene-exposed workers and in 60 referents was investigated. Colour vision was evaluated by adopting the Lanthony D 15 desaturated panel, a test specifically suited to detect mild acquired dyschromatopsia. The results of the test were expressed as the Colour Confusion Index. Styrene exposure was evaluated with both environmental and biological monitoring. Airborne levels of the solvent were 3.2 to 549.5mg/m3. In styrene-exposed workers colour vision was significantly impaired when compared with referents matched for age. A significative correlation was found between environmental and urinary levels of styrene and the Colour Confusion Index excluding the influence of age in multiple regression analysis, indicating the possibility of a dose-effect relationship. The findings suggest that styrene can induce an early appearance of a dose-dependent colour vision loss.
Descriptors (primary) visual function disorders; styrene; exposure evaluation; solvents; colour vision deficiency
Descriptors (secondary) vision tests; determination in urine; statistical evaluation; dose-response relationship
Document type D - Periodical articles
Country / State or ProvinceItaly
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the eye and vision damage
Aromatic hydrocarbons
Exposure evaluation