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Document ID (ISN)56946
CIS number 91-1932
ISSN - Serial title 0002-8894 - American Industrial Hygiene Association Journal
Year 1991
Convention or series no.
Author(s) Kononen D.W.
Title First-year changes in blood lead and zinc protoporphyrin levels within two groups of occupational lead workers
Bibliographic information Apr.1991, Vol.52, No.4, p.177-182. Illus. 9 ref.
Abstract Quarterly changes in the blood lead (PbB) and zinc protoporphyrin (ZPP) levels of 30 male lead-acid storage battery workers and 24 auto assembly workers during their first year of lead exposure are described. The greatest absolute and percentage increases above baseline PbB levels occurred during the first 3 months of continuous exposure when battery and assembly workers' average PbB levels increased by 99% and 134% respectively. Mean ZPP levels increased steadily through the first 3 quarters of exposure for both groups of workers before declining slightly in the last quarter. The PbB-ZPP dose-effect relationship is characterised through the simple linear regression of log-transformed ZPP versus PbB levels. Dose-response modeling of each quarter's PbB-ZPP data was performed using probit analysis. These observed PbB and ZPP changes illustrate the time lag in the appearance of ZPP following introduction to lead-related work.
Descriptors (primary) lead; storage batteries; motor vehicle industry; exposure; determination in blood; blood monitoring; zinc and compounds; length of exposure
Descriptors (secondary) effective dose 50; mathematical models; dose-response relationship; zinc
Document type D - Periodical articles
Country / State or ProvinceUSA
Subject(s) Occupational pathology
Broad subject area(s) Chemical safety
Browse category(ies) Inorganic substances
Biological monitoring
Motor vehicle manufacturing industry
Lead and compounds