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Document ID (ISN)56571
CIS number 91-1591
ISSN - Serial title 0914-3777 - Japanese Journal of Toxicology
Year 1991
Convention or series no.
Author(s) Yoshikawa H., Yoshida M., Ueda T., Yatsugi K., Hara I.
Title Evaluation of exposure to organophosphorus insecticides and of its effect on ocular function in pest control operators
Original title Bōeki sagyōsha ni okeru yūki rinzai bakuro no hyōka to sono gan kinō e no eikyō [in Japanese]
Bibliographic information 25 Jan. 1991, Vol.4, No.1, p.65-71. 12 ref.
Abstract Electroretinograms (ERG) were measured for 8 pest control operators to assess the effect of exposure to organophosphorus insecticides on ophthalmic function. One operator spraying chlorpyrifos 10 times per week showed marked decreases in plasma and erythrocyte cholinesterase (ChE) activity, the most subjective symptoms and an abnormal ERG with marked decreases in amplitudes of all the waves. Four operators spraying fenitrothion and dichlorvos 3-5 times per week showed low plasma and/or erythrocyte ChE activities. Among these operators, 2 showed ERG changes including decreased amplitudes of some waves, and 1 of them showed some subjective symptoms. Alkylphosphates were detected in the urine of all the operators. The abnormal ERG observed in the chlorpyrifos-sprayer may have been caused by exposure to this organophosphorus pesticide.
Descriptors (primary) chlorpyrifos; visual function disorders; exposure evaluation; crop protection; organophosphorus compounds
Descriptors (secondary) electroretinography; dichlorvos; metathion; insecticides; cholinesterase
Document type D - Periodical articles
Country / State or ProvinceJapan
Subject(s) Toxic and dangerous substances
Broad subject area(s) Chemical safety
Browse category(ies) Esters and salts
Exposure evaluation
Diseases of the eye and vision damage