|Document ID (ISN)||54976|
|Convention or series no.
||Arbete och hälsa 1989:25
||Garberg P., Högberg J., Lundberg I., Lundberg P.
||NIOH and NIOSH basis for an occupational health standard: Di(2-ethylhexyl)phthalate (DEHP)
||Arbetsmiljöinstitutet, Förlagstjänst, 171 84 Solna, Sweden, 1989. Also available from: Superintendent of Documents, US Government Printing Office, Washington D.C. 20402, USA. 53p. 131 ref.
||Literature survey on di(2-ethylhexyl)phthalate (DEHP), to be used as background information for discussions on occupational exposure limits in the USA and Sweden. Data on occupational exposure levels and effects on humans are limited. DEHP is hydrolysed to the monoethylhexyl product and further oxidised. No accumulation has been observed. DEHP has a low acute toxicity. Long-term exposure to rats causes testicular atrophy. DEHP is carcinogenic and teratogenic in rodents. Most genotoxicity tests have been negative. However, certain tests have indicated that DEHP may affect the genome in vitro.
||bis(ethylhexyl) phthalate; limitation of exposure; toxicology
||literature survey; Sweden; USA; testicular atrophy; criteria document; genetic effects; teratogenic effects; carcinogenic effects; determination of exposure limits
||F - Information notes, codes of practice, standards
|Country / State or Province||Sweden; USA|
||Toxic and dangerous substances
|Broad subject area(s)
||Genetic factors in reaction to exposures
Esters and salts