| Document ID (ISN) | 54131 |
| CIS number |
90-1269 |
| ISSN - Serial title |
0105-1873 - Contact Dermatitis |
| Year |
1989 |
| Convention or series no. |
|
| Author(s) |
Cavelier C., Foussereau J., Gille P., Zissu D. |
| Title |
Allergy to nickel or cobalt: Tolerance to nickel and cobalt samples in man and in the guinea pig allergic or sensitized to these metals |
| Bibliographic information |
Aug. 1989, Vol.21, No.2, p.72-78. 14 ref. |
| Abstract |
The aim of this study was to evaluate, in animals and humans sensitive to nickel or cobalt, the tolerance to manufactured metal samples of nickel and cobalt of a defined metallographic structure, plated or not with a layer of chrome or copper/chrome of a determined thickness. Under the defined experimental conditions, a guinea pig sensitised to one metal (nickel or cobalt) was intolerant to both metals (nickel and cobalt). A plating of chrome or copper/chrome did not act as a protection. In the human, it was not the same: the tolerance to metal samples was determined by the specific sensitivity. A plating of chrome or copper/chrome did not act as protection. |
| Descriptors (primary) |
cobalt; nickel; copper; sensitization; skin tests; chromium; skin allergies |
| Descriptors (secondary) |
animal experiments; dangerous substances |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Inorganic substances
Copper and compounds
Allergies
Skin diseases
Nickel and compounds
|
