| Document ID (ISN) | 53682 |
| CIS number |
90-594 |
| Year |
1989 |
| Convention or series no. |
DHHS (NIOSH) Publication No.90-101
|
| Title |
Current Intelligence Bulletin No.53 - Toluene diisocyanate (TDI) and toluenediamine (TDA): Evidence of carcinogenicity |
| Bibliographic information |
U.S. Department of Health and Human Services, Public Health Service, Centers for Disease Control, National Institute for Occupational Safety and Health, Division of Standards Development and Technology Transfer, 4676 Columbia Parkway, Cincinnati OH 45226, USA, 1989. 20p. Bibl. |
| Abstract |
Experimental studies have demonstrated that TDI and TDA (a hydrolysis product of TDI) are carcinogens. The test results meet both OSHA and NIOSH criteria for classifying a substance as a potential occupational carcinogen. NIOSH therefore recommends that all isomers of TDI and TDA be considered as potential carcinogens and that exposures be limited to the lowest feasible concentrations. |
| Descriptors (primary) |
carcinogens; tolylene diisocyanate; diaminotoluenes; USA |
| Descriptors (secondary) |
mutagenic effects; animal experiments; hazard evaluation; 2,4-diaminotoluene |
| Document type |
F - Information notes, codes of practice, standards |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Aromatic amines
Genetic factors in reaction to exposures
Isocyanates
Cyano compounds
|
