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CISDOC database

Document ID (ISN)53192
CIS number 90-123
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1989
Convention or series no.
Author(s) Paci E., Buiatti E., Seniori Costantini A., Miligi L., Pucci N., Scarpelli A., Petrioli G., Simonato L., Winkelmann R., Kaldor J.M.
Title Aplastic anemia, leukemia and other cancer mortality in a cohort of shoe workers exposed to benzene
Bibliographic information Oct. 1989, Vol.15, No.5, p.313-318. 15 ref.
Abstract This report presents the results of a historical cohort study in a shoe manufacturing plant in Florence where cases of aplastic anaemia and leukaemia were reported in the 1960s. A total of 1008 men and 1005 women were considered eligible members of the cohort. For total mortality, comparing the rates of the cohort with the national rates, the standardized mortality ratio (SMR) was 79 for the women and 95 for the men. For the men, excess of risk for aplastic anaemia (SMR 1566) and leukaemia (SMR 400) were observed. The increased risk occurred among workers first employed during the period in which benzene was used, but the expected number of cases in the subsequent period was too small to evaluate whether any reduction in risk had occurred. No increasing pattern with duration of employment was discernible.
Descriptors (primary) leukaemia; benzene; shoe industry; mortality; carcinogenic effects; aplastic anaemia
Descriptors (secondary) long-term study; comparative study; neoplasms; frequency rates
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s) Occupational medicine, epidemiology
Browse category(ies) Blood diseases
Aromatic hydrocarbons
Footwear, leather and fur industry
Leukaemia