| Document ID (ISN) | 52423 |
| CIS number |
89-1580 |
| ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
| Year |
1987 |
| Convention or series no. |
|
| Author(s) |
Šmidt P., Ivanov N.G. |
| Title |
Methodological approaches to the assessment of short-term exposure to industrial chemicals with hepatotoxic properties |
| Original title |
Metodočeskie podhody k ocenke gepatotropnogo dejstvija promyšlennyh veščestv pri kratkosročnom vozdejstvii [in Russian] |
| Bibliographic information |
Dec. 1987, No.12, p.33-36. Illus. 8 ref. |
| Abstract |
Animal experiments carried out to investigate changes in liver function as a result of short-term exposure to known hepatotoxic chemicals (carbon tetrachloride, allyl alcohol, styrene) and to new industrial chemical compounds (diallyl phthalate, diaminodiphenylmethane etc.) showed the need for standardisation of experimental conditions for determination of the threshold of acute action of toxic chemicals on liver function for the purposes of hygienic standardisation. A set of compulsory and additional tests for detecting hepatotoxic effects of occupational poisons under conditions of short-term exposure is recommended. |
| Descriptors (primary) |
methylenedianiline; allyl alcohol; hepatotoxic effects; standardization; styrene; diallyl phthalate; carbon tetrachloride |
| Descriptors (secondary) |
chloroform; 1,1,2,2-tetrachloroethane; diallyl isophthalate; short-term exposure; toxic substances; animal experiments; metabolic disturbances |
| Document type |
D - Periodical articles |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
Chemical safety
|
| Browse category(ies) |
Alcohols
Aromatic amines
Phthalates
Halogenated hydrocarbons
Aromatic hydrocarbons
Esters and salts
|
