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Document ID (ISN)49437
CIS number 88-563
ISSN - Serial title 0271-3586 - American Journal of Industrial Medicine
Year 1987
Convention or series no.
Author(s) Guay D., Siemiatycki J.
Title Historic cohort study in Montreal's fur industry
Bibliographic information 1987, Vol.12, No.2, p.181-193. 12 ref.
Abstract A historic cohort mortality study was carried out among 2 groups of male workers (mean age: 43.2 years; mean number of years since first employment: 14.1 years; follow-up after cohorts were established: 15 years) in the Montreal fur industry: 263 dressers and dyers and 599 fur garment workers. One group was exposed to a large variety of chemicals (including carcinogens and mutagens) used in tanning, cleaning, and dyeing fur, and the other to residue from the dressing and dyeing stage and to respirable fur dust. Observed deaths were compared with those expected based on mortality rates of the population of metropolitan Montreal. Standardised mortality ratios (SMRs) for the garment workers significantly low, probably because of the ethnic composition of the cohort and a healthy worker effect. SMRs for the dressers and dyers were also low, but not as low as for the garment workers. For French Canadians in the cohort, the observed deaths were close to the expected; there was a noteworthy excess of colorectal cancer (4 observed, 0.8 expected) for dressers and dyers. Apart from this weak suggestive evidence, results did not indicate any excess mortality risks in the fur industry. However, because of the relatively small number of expected and observed deaths in the cohort and especially among the heavily exposed dressers and dyers, confidence intervals around SMR estimates were wide and excess risks cannot be ruled out.
Descriptors (primary) fur industry; toxic substances
Descriptors (secondary) mutagenic effects; dangerous substances; mutagens; carcinogens; Canada; tanning agents; neoplasms; dyes; dust; tanning; dyeing; long-term study; carcinogenic effects; mortality
Document type D - Periodical articles
Subject(s) Leather, fur and footwear
Broad subject area(s) Chemical safety
Browse category(ies) Footwear, leather and fur industry
Genetic factors in reaction to exposures