ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)48299
CIS number 87-999
ISSN - Serial title 0025-7818 - Medicina del lavoro
Year 1987
Convention or series no.
Author(s) Soleo L., Coratelli A., Iacovone M.T., De Liso E., Margari L., Cassano F., Elia G., Fantuzzi A., Sassi C., Ambrosi L.
Title Neurophysiological study of a group of workers exposed to technical heptane in a rubber shoe factory
Original title Indagine neurofisiologica su un gruppo di lavoratori esposti ad eptano tecnico in una fabbrica di calzature in gomma [in Italian]
Bibliographic information Jan.-Feb. 1987, Vol.78, No.1, p.68-74. Illus. 25 ref.
Abstract This study involved 50 workers exposed to technical heptane and 2 groups of controls of roughly equal size. The technical heptane had the following composition: 38-40% n-heptane, 8-10% 3-methylhexane, 27-30% 2-methylhexane, 17-21% methylcyclohexane, <0.2% n-hexane and <3% other solvents (toluene, etc.). Exposure levels at work stations did not exceed TLV-TWA levels set by ACGIH for n-heptane. Nevertheless, in the exposed workers there was a significantly raised level of subclinical neuropathy involving the most distal sensitive tracts of the median nerve. Dysaesthesia and asthenia of the limbs were the most frequently noted subjective neurological symptoms among the exposed workers. No correlations were found between duration and extent of exposure to n-heptane and total technical heptane on one hand, and measured neurological functions on the other. It is recommended that TLVs be set for the components of technical heptane.
Descriptors (primary) rubber industry; organic solvents; shoe industry; impurities; heptane; neurological effects
Descriptors (secondary) hexane; 3-methylhexane; methylcyclohexane; 2-methylhexane; exposure evaluation; chemical hazards; toluene
Document type D - Periodical articles
Subject(s) Leather, fur and footwear
Broad subject area(s) Chemical safety
Browse category(ies) Diseases of the nervous system
Environmental pollution
Aliphatic and alicyclic hydrocarbons
Footwear, leather and fur industry
Rubber industry