|Document ID (ISN)||48299|
|ISSN - Serial title
||0025-7818 - Medicina del lavoro
|Convention or series no.
||Soleo L., Coratelli A., Iacovone M.T., De Liso E., Margari L., Cassano F., Elia G., Fantuzzi A., Sassi C., Ambrosi L.
||Neurophysiological study of a group of workers exposed to technical heptane in a rubber shoe factory
||Indagine neurofisiologica su un gruppo di lavoratori esposti ad eptano tecnico in una fabbrica di calzature in gomma [in Italian]|
||Jan.-Feb. 1987, Vol.78, No.1, p.68-74. Illus. 25 ref.
||This study involved 50 workers exposed to technical heptane and 2 groups of controls of roughly equal size. The technical heptane had the following composition: 38-40% n-heptane, 8-10% 3-methylhexane, 27-30% 2-methylhexane, 17-21% methylcyclohexane, <0.2% n-hexane and <3% other solvents (toluene, etc.). Exposure levels at work stations did not exceed TLV-TWA levels set by ACGIH for n-heptane. Nevertheless, in the exposed workers there was a significantly raised level of subclinical neuropathy involving the most distal sensitive tracts of the median nerve. Dysaesthesia and asthenia of the limbs were the most frequently noted subjective neurological symptoms among the exposed workers. No correlations were found between duration and extent of exposure to n-heptane and total technical heptane on one hand, and measured neurological functions on the other. It is recommended that TLVs be set for the components of technical heptane.
||rubber industry; organic solvents; shoe industry; impurities; heptane; neurological effects
||hexane; 3-methylhexane; methylcyclohexane; 2-methylhexane; exposure evaluation; chemical hazards; toluene
||D - Periodical articles
||Leather, fur and footwear
|Broad subject area(s)
||Diseases of the nervous system
Aliphatic and alicyclic hydrocarbons
Footwear, leather and fur industry