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Document ID (ISN)46435
CIS number 86-1367
ISSN - Serial title 0049-8610 - Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete
Year 1985
Convention or series no.
Author(s) Bittersohl K.U., Bittersohl G.
Title Epidemiological investigations into the haematotoxic and hepatotoxic effects of benzene and benzene-containing mixed solvents
Original title Epidemiologische Untersuchungen zur hämatotoxischen und hepatotoxischen Wirkung von Benzen und benzenhaltigen Lösungsmittelgemischen [in German]
Bibliographic information 1985, Vol.31, No.3, p.168-170. Illus. 30 ref.
Abstract An assessment of the data on 85 persons newly registered between 1973 and 1982 as suffering from occupational disease due to exposure to benzene has shown that this intoxication occurs primarily in the chemical and shoemaking industries. The disease has to be considered severe, because >20% of the affected persons have a disability of > 50% and/or die of the consequences of the intoxication. The mean exposure time was 15.2 (2-38) years. Only 16% of the persons newly registered as suffering from this occupational disease had been exposed to benzene alone. All the other persons were exposed to mixed solvents. After elimination of the persons who were abusing alcohol and those suffering from previous non-occupational lesions, the assessment reaffirms the haematotoxic effect of benzene; liver lesions are the result of the simultaneous effect of other solvents, especially alcohols. No hepatotoxic effect can be attributed to benzene.
Descriptors (primary) chemical industry; hepatotoxic effects; alcohols; shoe industry; organic solvents; haematotoxic effects; benzene
Descriptors (secondary) length of exposure; epidemiologic study
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Chemical industry
Aromatic hydrocarbons
Footwear, leather and fur industry