|Document ID (ISN)||46435|
|ISSN - Serial title
||0049-8610 - Zeitschrift für die gesamte Hygiene und ihre Grenzgebiete
|Convention or series no.
||Bittersohl K.U., Bittersohl G.
||Epidemiological investigations into the haematotoxic and hepatotoxic effects of benzene and benzene-containing mixed solvents
||Epidemiologische Untersuchungen zur hämatotoxischen und hepatotoxischen Wirkung von Benzen und benzenhaltigen Lösungsmittelgemischen [in German]|
||1985, Vol.31, No.3, p.168-170. Illus. 30 ref.
||An assessment of the data on 85 persons newly registered between 1973 and 1982 as suffering from occupational disease due to exposure to benzene has shown that this intoxication occurs primarily in the chemical and shoemaking industries. The disease has to be considered severe, because >20% of the affected persons have a disability of > 50% and/or die of the consequences of the intoxication. The mean exposure time was 15.2 (2-38) years. Only 16% of the persons newly registered as suffering from this occupational disease had been exposed to benzene alone. All the other persons were exposed to mixed solvents. After elimination of the persons who were abusing alcohol and those suffering from previous non-occupational lesions, the assessment reaffirms the haematotoxic effect of benzene; liver lesions are the result of the simultaneous effect of other solvents, especially alcohols. No hepatotoxic effect can be attributed to benzene.
||chemical industry; hepatotoxic effects; alcohols; shoe industry; organic solvents; haematotoxic effects; benzene
||length of exposure; epidemiologic study
||D - Periodical articles
|Broad subject area(s)
Footwear, leather and fur industry