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Document ID (ISN)45287
CIS number 86-140
ISSN - Serial title 0340-0131 - International Archives of Occupational and Environmental Health
Year 1984
Convention or series no.
Author(s) Perbellini L., Brugnone F., Mozzo P., Cocheo V., Caretta D.
Title Methyl ethyl ketone exposure in industrial workers - Uptake and kinetics
Bibliographic information 1984, Vol.54, No.1, p.73-81. Illus. 10 ref.
Abstract Very little data being available on the uptake, distribution, biotransformation and elimination of methyl ethyl ketone (MEK), the present study compares alveolar concentrations of MEK with exposure and with blood MEK concentrations. Urinary excretion of MEK and its metabolite, acetylmethylcarbinol, was also compared with exposure. The solubility of MEK in body tissues and a multicompartmental model allowed the estimation of the distribution and kinetics of MEK.
Descriptors (primary) butanone; excretion; solubility in body tissues; body retention; shoe industry
Descriptors (secondary) inhalation; adhesives; organic solvents; shoemakers; mathematical models; exposure tests; urinary metabolites
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Ketones
Footwear, leather and fur industry