ILO Home
Go to the home page
Site map | Contact us Franšais | Espa˝ol

CISDOC database

Document ID (ISN)44705
CIS number 85-1623
ISSN - Serial title 0098-4108 - Journal of Toxicology and Environmental Health
Year 1985
Convention or series no.
Author(s) Alexeeff G.V., Kilgore W.W., Mu˝oz P., Watt D.
Title Determination of acute toxic effects in mice following exposure to methyl bromide
Bibliographic information 1985, Vol.15, No.1, p.109-123. Illus. 23 ref.
Abstract Mice were exposed for 1h to concentrations of methyl bromide ranging from 0.87 to 5.93mg/L. Decreased lung and liver weights were observed at 2.20 and 2.70mg/L, kidney lesions appeared at 3.50mg/L and mortality occurred at 3.82mg/L and above. The 1h LC50 of methyl bromide in mice via inhalation was 4.68mg/L (about 1200ppm). The dose-response curve was very steep and the LC10 to LC90 range of mortality was contained within a doubling of concentration.
Descriptors (primary) methyl bromide; toxicology; lethal concentration 50; renal diseases; fumigants
Descriptors (secondary) inhalation toxicity; animal experiments
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Halogenated hydrocarbons
Agricultural chemicals