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Document ID (ISN)44228
CIS number 85-1092
ISSN - Serial title 0098-4108 - Journal of Toxicology and Environmental Health
Year 1984
Convention or series no.
Author(s) Wester R.C., Maibach H.I., Bucks D.A.W., Aufrere M.B.
Title In vivo percutaneous absorption of paraquat from hand, leg and forearm of humans
Bibliographic information 1984, Vol.14, No.5-6, p.759-762. 10 ref.
Abstract 3 skin sites of application were used in a crossover manner for 6 subjects. Radiolabelled paraquat was used to measure the absorption. The percentages of applied dose (9Ág/cm2) absorbed were 0.29▒0.2 for the leg, 0.23▒0.1 for the hand and 0.29▒0.1 for the forearm. The in vivo absorption rate was 0.03Ág/cm2 for a 24h exposure. Paraquat absorption through the intact skin seems to be minimal when compared to inhalation or ingestion.
Descriptors (primary) paraquat; agriculture; skin absorption
Descriptors (secondary) human experiments
Document type D - Periodical articles
Subject(s) Agriculture, fishing, animal husbandry
Broad subject area(s)
Browse category(ies) Heterocyclic compounds