| Document ID (ISN) | 44228 |
| CIS number |
85-1092 |
| ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
| Year |
1984 |
| Convention or series no. |
|
| Author(s) |
Wester R.C., Maibach H.I., Bucks D.A.W., Aufrere M.B. |
| Title |
In vivo percutaneous absorption of paraquat from hand, leg and forearm of humans |
| Bibliographic information |
1984, Vol.14, No.5-6, p.759-762. 10 ref. |
| Abstract |
3 skin sites of application were used in a crossover manner for 6 subjects. Radiolabelled paraquat was used to measure the absorption. The percentages of applied dose (9µg/cm2) absorbed were 0.29±0.2 for the leg, 0.23±0.1 for the hand and 0.29±0.1 for the forearm. The in vivo absorption rate was 0.03µg/cm2 for a 24h exposure. Paraquat absorption through the intact skin seems to be minimal when compared to inhalation or ingestion. |
| Descriptors (primary) |
paraquat; agriculture; skin absorption |
| Descriptors (secondary) |
human experiments |
| Document type |
D - Periodical articles |
| Subject(s) |
Agriculture, fishing, animal husbandry
|
| Broad subject area(s) |
|
| Browse category(ies) |
Heterocyclic compounds
Agriculture
|
