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Document ID (ISN)42603
CIS number 84-1672
ISSN - Serial title 0355-3140 - Scandinavian Journal of Work, Environment and Health
Year 1983
Convention or series no.
Author(s) Sj÷gren B., Hedenstierna G.
Title Pulmonary function and concentrations of alpha1-antitrypsin and immunoglobulin E in workers exposed to pancreatic enzymes
Bibliographic information Oct. 1983, Vol.9, No.5, p.385-390. 28 ref.
Abstract 14 male workers exposed to pancreatic enzymes in a tannery, and a group of 14 non-exposed referents matched for age, sex, height and smoking habits, were studied by interview, spirometry and the single-breath nitrogen washout technique. Symptoms in the airways were reported by 7 of the subjects when weighing pancreatic enzymes. The exposed group did not show any deterioration in pulmonary volumes, forced expiratory flow, airway closure, or gas distribution when compared to the referents, and the serum levels of IgE did not differ between the groups. The exposed group had significantly higher plasma levels of α1-antitrypsin, possibly due to a compensatory response to increased levels of proteases within the lungs.
Descriptors (primary) antitrypsin; tanning industry; enzymes; proteases
Descriptors (secondary) immunoglobulin changes; exposure evaluation; pulmonary function
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Footwear, leather and fur industry