|Document ID (ISN)||42438|
|Convention or series no.
||Arbete och hńlsa 1982:32
||Bellander T., Hagmar L.
||Morfolin [in Swedish]|
||Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1982. 32p. 92 ref.
||Criteria document based on literature data. Morpholine is a cyclic secondary amine with corrosive and irritant action. It is readily taken up by the skin, and is excreted in the urine unchanged. High concentrations are required to produce effects in toxicological experiments. Morpholine is not mutagenic, but it is readily converted to the mutagenic N-nitrosomorpholine in the presence of nitrites in vitro and in vivo. Evaluation of morpholine exposure must thus take account of exposure to potential nitrosating agents such as nitrites or nitrous oxide.
||N-nitrosomorpholine; harmful substances; toxicology; morpholine
||literature survey; mutagens; corrosive substances; nephrotoxic effects; carcinogens; hepatotoxic effects; irritants
||E - Books, reports, proceedings
||Toxic and dangerous substances
|Broad subject area(s)