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Document ID (ISN)42438
CIS number 84-1316
ISBN(s) 91-7464-151-4
Year 1982
Convention or series no. Arbete och hńlsa 1982:32
Author(s) Bellander T., Hagmar L.
Title Morpholine
Original title Morfolin [in Swedish]
Bibliographic information Arbetarskyddsstyrelsen, Publikationsservice, 171 84 Solna, Sweden, 1982. 32p. 92 ref.
Abstract Criteria document based on literature data. Morpholine is a cyclic secondary amine with corrosive and irritant action. It is readily taken up by the skin, and is excreted in the urine unchanged. High concentrations are required to produce effects in toxicological experiments. Morpholine is not mutagenic, but it is readily converted to the mutagenic N-nitrosomorpholine in the presence of nitrites in vitro and in vivo. Evaluation of morpholine exposure must thus take account of exposure to potential nitrosating agents such as nitrites or nitrous oxide.
Descriptors (primary) N-nitrosomorpholine; harmful substances; toxicology; morpholine
Descriptors (secondary) literature survey; mutagens; corrosive substances; nephrotoxic effects; carcinogens; hepatotoxic effects; irritants
Document type E - Books, reports, proceedings
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Heterocyclic compounds