| Document ID (ISN) | 42023 |
| CIS number |
84-1053 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1983 |
| Convention or series no. |
|
| Author(s) |
Hasegawa K., Shiojima S., Koizumi A., Ikeda M. |
| Title |
Hippuric acid and o-cresol in the urine of workers exposed to toluene |
| Bibliographic information |
1983, Vol.52, No.3, p.197-208. Illus. 33 ref. |
| Abstract |
74 male and 56 female factory workers were studied. Correlation co-efficients between the TWA toluene concentration in the air and urinary excretion suggested that hippuric acid is a better index of toluene exposure than o-cresol. There was a significant correlation between o-cresol and hippuric acid in respect of the increase in urinary levels as a function of exposure. In 8 female workers, the slopes of the regression lines between o-cresol and hippuric acid in the urine were identical regardless of variation in exposure intensity. An individual difference exists in the pattern of toluene metabolism which is presumably set congenitally. The possible toxicological significance is discussed. |
| Descriptors (primary) |
cresols; toluene; exposure tests; urinary metabolites; hippuric acid |
| Descriptors (secondary) |
cresylic acid; rubber industry; printing industry; individual variables; metabolic process; comparative study; women; dose-response relationship; urine monitoring; shoe industry; toxicology |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Alcohols
Biological monitoring
Aromatic hydrocarbons
|
