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CISDOC database
Document ID (ISN) | 41994 |
CIS number |
84-1000 |
Year |
1983 |
Convention or series no. |
DHHS (NIOSH) Publication No.84-104
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Title |
2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, "dioxin") |
Bibliographic information |
U.S. Department of Health and Human Services, NIOSH, Robert A. Taft Laboratories, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, 23 Jan. 1984. 22p. 88 ref. |
Abstract |
In animals, TCDD causes tumorigenesis, immunological dysfunction and teratogenesis at a wide range of exposure concentrations, and evidence exists to suggest carcinogenicity. In humans, TCDD exposure has caused chloracne, metabolic disorders, e.g. porphyria, and other systemic problems. TCDD occurs as a contaminant of chlorophenols and chlorophenoxyacetic acids. TCDD should be regarded as a potential occupational carcinogen, and exposure should be controlled to the fullest extent feasible. Decontamination measures must be used for TCDD-contaminated workplaces. |
Descriptors (primary) |
carcinogens; biological effects; tetrachlorodibenzodioxin; USA |
Descriptors (secondary) |
phenoxyacetic acids; porphyria; directive; limitation of exposure; teratogenic effects; chloracne |
Document type |
F - Information notes, codes of practice, standards |
Subject(s) |
Toxic and dangerous substances
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Broad subject area(s) |
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Browse category(ies) |
Genetic factors in reaction to exposures Heterocyclic compounds
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