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CISDOC database

Document ID (ISN)41994
CIS number 84-1000
Year 1983
Convention or series no. DHHS (NIOSH) Publication No.84-104
Title 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD, "dioxin")
Bibliographic information U.S. Department of Health and Human Services, NIOSH, Robert A. Taft Laboratories, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, 23 Jan. 1984. 22p. 88 ref.
Abstract In animals, TCDD causes tumorigenesis, immunological dysfunction and teratogenesis at a wide range of exposure concentrations, and evidence exists to suggest carcinogenicity. In humans, TCDD exposure has caused chloracne, metabolic disorders, e.g. porphyria, and other systemic problems. TCDD occurs as a contaminant of chlorophenols and chlorophenoxyacetic acids. TCDD should be regarded as a potential occupational carcinogen, and exposure should be controlled to the fullest extent feasible. Decontamination measures must be used for TCDD-contaminated workplaces.
Descriptors (primary) carcinogens; biological effects; tetrachlorodibenzodioxin; USA
Descriptors (secondary) phenoxyacetic acids; porphyria; directive; limitation of exposure; teratogenic effects; chloracne
Document type F - Information notes, codes of practice, standards
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Genetic factors in reaction to exposures
Heterocyclic compounds