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Document ID (ISN)41843
CIS number 84-817
Year 1982
Convention or series no.
Author(s) Falck K.
Title Application of the bacterial urinary mutagenicity assay in detection of exposure to genotoxic chemicals
Bibliographic information Institute of Occupational Health, Haartmaninkatu 1, 00290 Helsinki 29, Finland, 1982. 92p. Illus. 115 ref.
Abstract This academic dissertation is based on data given in 10 published articles. Studies discussed concerned workers in a hospital oncology unit, the rubber industry, and iron foundries. Nurses preparing cytostatic drugs had mutagenic activity in their urine, which was much lower than in patients receiving the drugs, and which decreased when contermeasures were taken. Workers of both the other groups also had mutagenic activity in their urine. In a separate study, smokers, too, showed urinary mutagenic activity. The final 50 pages of the monograph contain reproductions of the articles reviewed.
Descriptors (primary) mutagens; carcinogens; rubber industry; foundries; chemical products; mutagenicity tests; hospitals; drugs
Descriptors (secondary) literature survey; Finland; determination in urine; thesis; smoking
Document type E - Books, reports, proceedings
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Rubber industry
Health care services
Foundries, metalcasting and forging operations