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Document ID (ISN)40717
CIS number 83-1959
ISSN - Serial title 0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku
Year 1982
Convention or series no.
Author(s) Ohashi Y., Nakai Y., Harada H., Horiguchi S., Teramoto K., Katahira T.
Title Experimental studies on the mucosal membrane of respiratory tracts of rats exposed to tetrahydrofuran
Bibliographic information 1982, Vol.24, No.5, p.485-497. Illus. 17 ref.
Abstract Morphological changes and altered ciliary functions were observed after exposure to 100 and 5000ppm tetrahydrofuran (THF). The number of ciliary beats showed little or no decrease from control levels on exposure to THF at either concentration for 1 day. The number of beats decreased progressively for exposures of 1 week or more and the decrease was greater at the 5000ppm exposure level. Morphological changes in, and damage to, the tracheal mucosal epithelium followed a similar pattern.
Descriptors (primary) tetrahydrofuran; biological effects; mucous membranes; upper respiratory tract
Descriptors (secondary) respiratory impairment; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Heterocyclic compounds