Document ID (ISN) | 40417 |
CIS number |
83-1609 |
ISSN - Serial title |
Gigiena truda i professional'nye zabolevanija |
Year |
1981 |
Convention or series no. |
|
Author(s) |
Vasilenko N.M., Zvezdaj V.I. |
Title |
Possibility of mathematical prediction of some criteria of toxicity of nitro and amino benzenoid compounds |
Original title |
Vozmožnosti matematičesko prognozirovanija nekotoryh kriteriev toksičnosti nitro- i aminosoedinenij benzol'nogo rjada [in Russian] |
Bibliographic information |
Aug. 1981, No.8, p.50-52. |
Abstract |
Tabulation of the LD50 values of 22 aminobenzenoids and 21 nitrobenzenoids showed that their acute toxicities increase with increasing molecular weight; coefficients of linear regression equations expressing this relationship were calculated. Two-factor and multifactor correlation analysis also revealed correlations between LD50 and the levels of haemoglobin, oxyhaemoglobin, methaemoglobin and sulfhaemoglobin in the blood of experimental animals. |
Descriptors (primary) |
aromatic amines; aromatic nitro compounds; prediction formulae; toxicology |
Descriptors (secondary) |
haemoglobin; animal experiments; mathematical analysis; haematotoxic effects; lethal dose 50 |
Document type |
D - Periodical articles |
Subject(s) |
Toxic and dangerous substances
|
Broad subject area(s) |
|
Browse category(ies) |
Aliphatic nitro compounds Aromatic amines
|