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Document ID (ISN)39933
CIS number 83-1007
ISSN - Serial title 0047-1879 - Japanese Journal of Industrial Health - Sangyō-Igaku
Year 1982
Convention or series no.
Author(s) Katahira T., Teramoto K., Horiguchi S.
Title Experimental studies on the toxicity of tetrahydrofuran administered to animals by repeated inhalation
Bibliographic information 1982, Vol.24, No.4, p.379-387. Illus. 37 ref.
Abstract Rats were exposed to 100, 200, 1000 or 5000ppm tetrahydrofuran for 4h/day for 12 weeks. 100 and 200ppm had no significant effects except for slight mucosal irritation. 1000ppm affected liver function as indicated by serum chemistry tests. 5000ppm caused marked local irritant symptoms and morphological damage of the respiratory mucosae, and affected white blood cell counts, blood sugar levels and liver functions.
Descriptors (primary) tetrahydrofuran; inhalation toxicity; chronic toxicity; organic solvents
Descriptors (secondary) hepatotoxic effects; animal experiments; irritation
Document type D - Periodical articles
Subject(s) Toxic and dangerous substances
Broad subject area(s)
Browse category(ies) Heterocyclic compounds