Document ID (ISN) | 39908 |
CIS number |
83-1076 |
ISSN - Serial title |
0098-4108 - Journal of Toxicology and Environmental Health |
Year |
1982 |
Convention or series no. |
|
Author(s) |
Ashley W.M., Smith R.E., Dalvi R.R. |
Title |
Hepatotoxicity of orally and intraperitoneally administered folpet in male rats |
Bibliographic information |
May-June 1982, Vol.9, No.5-6, p.867-876. Illus. 15 ref. |
Abstract |
An intraperitoneal (i.p.) LD50 of 68mg/kg was determined in rats. 50mg/kg i.p. significantly altered the levels of enzymes reflecting liver damage, while up to 10 times this dose produced no such effects or toxic symptoms when given orally. In vitro studies with rat liver microsomes are reported. |
Descriptors (primary) |
hepatotoxic effects; fungicides; toxicology; folpet |
Descriptors (secondary) |
metabolic process; lethal dose 50; animal experiments |
Document type |
D - Periodical articles |
Subject(s) |
Occupational pathology
|
Broad subject area(s) |
|
Browse category(ies) |
Heterocyclic compounds Agricultural chemicals
|