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Document ID (ISN)39908
CIS number 83-1076
ISSN - Serial title 0098-4108 - Journal of Toxicology and Environmental Health
Year 1982
Convention or series no.
Author(s) Ashley W.M., Smith R.E., Dalvi R.R.
Title Hepatotoxicity of orally and intraperitoneally administered folpet in male rats
Bibliographic information May-June 1982, Vol.9, No.5-6, p.867-876. Illus. 15 ref.
Abstract An intraperitoneal (i.p.) LD50 of 68mg/kg was determined in rats. 50mg/kg i.p. significantly altered the levels of enzymes reflecting liver damage, while up to 10 times this dose produced no such effects or toxic symptoms when given orally. In vitro studies with rat liver microsomes are reported.
Descriptors (primary) hepatotoxic effects; fungicides; toxicology; folpet
Descriptors (secondary) metabolic process; lethal dose 50; animal experiments
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Heterocyclic compounds
Agricultural chemicals