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Document ID (ISN)38412
CIS number 82-1668
ISSN - Serial title 0386-3530 - Hokuriku Journal of Public Health - Hokuriku Koshu Eisei Gakkaishi
Year 1981
Convention or series no.
Author(s) Kawahara K., Samamoto M., Kushihata T.
Title Correlation between renal dysfunction and imino acid in cadmium poisoning. 1. Urinary findings of copper and/or cadmium-administered rats for three months
Bibliographic information Oct. 1981, Vol.8, No.1, p.14-18. 16 ref. Price: Y.2000.
Abstract In rats receiving copper (Cu) and/or cadmium (Cd), high correlation coefficients were found between (1) urinary Cd and both protein and free proline; (2) between urinary total proline and both free proline and free hydroxyproline; (3) between urinary Cd and calcium in the femur; and (4) between urinary proline and protein. Correlation was found between urinary imino acids in rats receiving 200ppm of Cu and Cd simultaneously or 200ppm of Cu alone. Urinary Cd, protein and glucose, and total and free proline can be used for early detection of chronic Cd poisoning.
Descriptors (primary) renal dysfunction; copper; cadmium; chronic poisoning; urine monitoring; amino acids
Descriptors (secondary) hydroxyproline; proteins; proline; exposure tests; urinary metabolites; animal experiments; early diagnosis
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Diseases of the kidney and the urinary system
Biological monitoring
Copper and compounds
Cadmium and compounds
Inorganic substances