| Document ID (ISN) | 37768 |
| CIS number |
82-1070 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Briatico-Vangosa G., Beretta F., Bianchi S., Cardani A., Marchisio M., Nava C., Talamo F. |
| Title |
Bronchial asthma due to 7-aminocephalosporanic acid in workers employed in cephalosporine production |
| Original title |
Asma bronchiale da acido 7-aminocefalosporanico (7-ACA) in lavoratori addetti alla produzione di cefalosporine [in Italian] |
| Bibliographic information |
Nov.-Dec. 1981, Vol.72, No.6, p.488-493. Illus. 20 ref. |
| Abstract |
In 91 workers involved in the production of cephalosporine, exposure to the intermediate 7-aminocephalosporanic acid caused bronchial asthma in 7, urticaria in 3 and dermatitis in 8. The recurrent positive results of the on-off test, clinical conditions, and the immediate positive skin reactions in 5 of the 7 asthmatic subjects following direct skin tests were good evidence that this substance was asthmatogenic and immunogenic. A methodology for identification of occupational risk and impairment is described. |
| Descriptors (primary) |
allergens; aminocephalosporanic acid; pharmaceutical industry; biological effects; asthma |
| Descriptors (secondary) |
sensitization dermatitis; urticaria; eczema; allergic asthma |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Pharmaceutical industry
Diseases of the respiratory system (except for pneumoconiosis & similar)
Heterocyclic compounds
|
