| Document ID (ISN) | 37465 |
| CIS number |
82-817 |
| ISSN - Serial title |
0323-9179 - Problemi na higienata |
| Year |
1981 |
| Convention or series no. |
|
| Author(s) |
Mirkova E., Ivanov I. |
| Title |
Embryotoxic effects of a triazine herbicide (Polizin 50) |
| Original title |
Vărhu embriotropnoto dejstvie na triazinovija herbicid polizin 50 [in Bulgarian] |
| Bibliographic information |
July 1981, Vol.6, p.36-43. Illus. 9 ref. |
| Abstract |
The embryotropic effect of the new Bulgarian simtriazine herbicide Polizin 50 was studied in an inhalatory experiment with 90 pregnant white Wistar rats in concentrations of 2mg/m3 and 0.2mg/m3 daily during the entire pregnancy and at a level of 2mg/m3 during the first 3 weeks of gestation. With both regimes, the preparation showed teratogenic and, to a lesser extent, embryotoxic effects. Polizin induces external malformations, anomalies in the development of the internal organs and defects in the ossificatin of the cranial bones of the foetus. The preparation has an embryotoxic activity only with daily penetration in the organism of the pregnant animals at a concentration of 2mg/m3. It is recommended that the employment of women in the production of this herbicide should be prohibited. |
| Descriptors (primary) |
embryotoxic effects; triazines; herbicides |
| Descriptors (secondary) |
triazene; animal experiments; prohibited work; women; expectant mothers; teratogenic effects |
| Document type |
D - Periodical articles |
| Subject(s) |
Agriculture, fishing, animal husbandry
|
| Broad subject area(s) |
|
| Browse category(ies) |
Agricultural chemicals
Genetic factors in reaction to exposures
Heterocyclic compounds
|
