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CISDOC database
| Document ID (ISN) | 37445 |
| CIS number |
82-744 |
| ISSN - Serial title |
0025-7818 - Medicina del lavoro |
| Year |
1981 |
| Convention or series no. |
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| Author(s) |
Suciu I., Prodan L., Lazar V., Ilea E., Cicīrla A., Olinici L., Paduraru A., Zagreanu O., Lengyel P., Györffi L., Andru D. |
| Title |
Research on copper poisoning |
| Bibliographic information |
May-June 1981, Vol.72, No.3, p.190-197. 8 ref. |
| Abstract |
Yearly examinations were performed on 75-100 workers involved in grinding and sieving copper (Cu) dust, over a 4 year period. 4 stages of Cu poisoning were identified. In the first stage the serum Cu was > 80µg%, with increased alpha-2-globulins, red bloodcells and haemoglobin. There was also hepatomegaly, gingivitis and a yellowish green line on the gums. In the second stage nervous disorders, gastro-intestinal disorders with hepatomegaly, anorexia, nausea, vomiting, and congestion of the face were also observed. Chronic irritative bronchitis, with yellowish green sputum, sexual impotency and non-secretory adenoma of the hypophysis with modifications of the sella turcica also occurred. The third stage was characterised by the appearance of organic lesions, sensitive polyneuritis and chronic hepatitis. In the 4th stage the organic symptoms were decompensated. Cu elimination from the body was obtained with D-penicillamine and chelation treatment. |
| Descriptors (primary) |
copper; chronic poisoning; respirable dust |
| Descriptors (secondary) |
hepatic damage; respiratory impairment; dyspnoea; functional digestive disorders; neurasthenia; bronchitis; pituitary disorders; gingivitis; hepatitis; polyneuritis; impotence; neurological effects; electrical industry; chelation therapy; symptoms |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
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| Broad subject area(s) |
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| Browse category(ies) |
Copper and compounds
Inorganic substances
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