| Document ID (ISN) | 36617 |
| CIS number |
81-2001 |
| ISSN - Serial title |
0340-0131 - International Archives of Occupational and Environmental Health |
| Year |
1980 |
| Convention or series no. |
|
| Author(s) |
Ferry D.G., Temple W.A., McQueen E.G. |
| Title |
Methanol monitoring - Comparison of urinary methanol concentration with formic acid excretion rate as a measure of occupational exposure |
| Bibliographic information |
Nov. 1980, Vol.47, No.2, p.155-163. 12 ref. |
| Abstract |
Methods of monitoring occupational exposure to methanol were investigated in volunteers with methanol ingestion. Urinary methanol concentrations accurately reflected those in the blood over a considerable range of concentrations. Urinary formic acid concentration (in µg/ml) was too variable but rate of urinary excretion of formic acid (in µg/min) did reflect methanol uptake. The ratio of urinary formic acid to creatinine concentrations is a practical monitoring method. However formic acid elimination rate is reduced by ingestion of alcoholic beverages. Urinary methanol concentration is favoured as a method of monitoring, and a concentration of 10µg/ml measured at the end of the work shift is suggested as the limit above which occupational exposure should be suspected and the appropriate action taken. |
| Descriptors (primary) |
methanol; exposure tests; fuelling; urinary excretion |
| Descriptors (secondary) |
urine monitoring; formic acid |
| Document type |
D - Periodical articles |
| Subject(s) |
Occupational pathology
|
| Broad subject area(s) |
|
| Browse category(ies) |
Biological monitoring
Alcohols
|
