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Document ID (ISN)35834
CIS number 81-1102
ISSN - Serial title 0098-4108 - Journal of Toxicology and Environmental Health
Year 1981
Convention or series no.
Author(s) Benjamin T., Evarts R.P., Reddy T.V., Weisburger E.K.
Title Effect of 2,2'-diaminodiphenyl disulfide, a resin hardener, on rats.
Bibliographic information Jan. 1981, Vol.7, No.1, p.69-81. Illus. 25 ref.
Abstract 2,2'-Diaminodiphenyl disulfide (DDDS) was developed as a substitute for 4,4'-methylenebis(2-chloroaniline). In rats DDDS caused changes in the liver, forestomach, and kidney. There was one case of hepatocellular carcinoma. Phospholipid pattern changes of the liver, kidney, and spleen occurred. DDDS was not mutagenic in a Salmonella test system.
Descriptors (primary) diaminodiphenyldisulfide; plastics industry; hardeners
Descriptors (secondary) animal experiments; substitution
Document type D - Periodical articles
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Chemical industry
Aromatic amines
Plastics industry