Document ID (ISN) | 33127 |
CIS number |
80-510 |
ISSN - Serial title |
0003-0805 - American Review of Respiratory Disease |
Year |
1979 |
Convention or series no. |
|
Author(s) |
Nelson L.A., Callerame M.L., Schwartz R.H. |
Title |
Aspergillosis and atopy in cystic fibrosis. |
Bibliographic information |
Oct. 1979, Vol.120, No.4, p.863-873. Illus. 47 ref. |
Abstract |
46 patients with cystic fibrosis (CF) were studied for colonisation and sensitisation by Aspergillus organisms. Aspergillus precicitins were found in 37% of CF patients; positive skin tests were found in 39%; atopy defined by skin test criteria was found in 46%. All of these findings were more common in patients with severe disease (P<0.05). CF patients had predominant mould sensitivity in contrast to predominant pollen sensitivity in a control group of asthmatic subjects. Serum IgE concentrations were increased in 22% of CF patients; 4 patients fulfilled the diagnostic criteria for allergic bronchopulmonary aspergillosis (ABPA) during the time of study and follow-up, and another patient had ABPA diagnosed before the study. The incidence of ABPA during a 2-year period in the CF population was 11%. |
Descriptors (primary) |
Aspergillus moulds; aspergillosis; allergic respiratory disorders; immunology; pulmonary fibrosis |
Descriptors (secondary) |
USA; case study; serological reactions; skin tests; hypersensitivity; survey |
Document type |
- |
Subject(s) |
Agriculture, fishing, animal husbandry
|
Broad subject area(s) |
|
Browse category(ies) |
Diseases of the respiratory system (except for pneumoconiosis & similar) Mycoses Bacterial and parasitic diseases Allergies
|