|
|
 |
|
|
CISDOC database
| Document ID (ISN) | 32461 |
| CIS number |
79-1945 |
| Year |
1979 |
| Convention or series no. |
|
| Author(s) |
Price N.H., Yates W.G., Allen S.D., Waters S.W. |
| Title |
Toxicity evaluation for establishing IDLH values. |
| Bibliographic information |
TR 1518-005, National Institute for Occupational Safety and Health, 4676 Columbia Parkway, Cincinnati, Ohio 45226, USA, 244p. Illus. 58 ref. |
| Abstract |
Animals were exposed for 14 days in whole body inhalation chambers to 2-aminoethanol, diisopropylamine, 2-diethylaminoethanol, o-toluidine, o- and p-anisidine, stibine, phosgene, diazomethane and Aroclor 1254; body weight was monitored. Control animals were treated in similar chambers. Symptoms noted were ataxia, tremors, respiratory distress and/or death. Irreversible pathological lesions were found in some organs, but not all could be ascribed to the exposure. Compounds that were liquid or solid were presented as vapours or aerosols if the vapour pressures were too low. Analytical methods for measurement of air concentrations are detailed. These substances have been reported as immediately hazardous to workers exposed to sufficiently high concentrations. The "Immediately Dangerous to Life or Health" (ILDH) level causes no harmful effects for up to 30min exposure. |
| Descriptors (primary) |
stibine; phosgene; polychlorinated biphenyls; amino alcohols; aliphatic amines; aromatic amines; toxicology; azo compounds |
| Descriptors (secondary) |
diazomethane; USA; report; Aroclor 1254; p-anisidine; o-toluidine; determination in air; diethylaminoethanol; diisopropylamine; o-anisidine; harmful substances; animal experiments; inhalation toxicity; ethanolamine |
| Document type |
E - Books, reports, proceedings |
| Subject(s) |
Toxic and dangerous substances
|
| Broad subject area(s) |
|
| Browse category(ies) |
Inorganic substances
Halogenated hydrocarbons
Aromatic amines
Aliphatic amines
|
|
|
|
|
|
