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Document ID (ISN)31214
CIS number 79-787
ISSN - Serial title 0343-2432 - Dermatosen in Beruf und Umwelt
Year 1978
Convention or series no.
Author(s) Weirich E.G.
Title Contact acne - Example of a dermatosis of civilisation
Original title Die Kontaktakne: Beispiel einer Zivilisationsdermatose [in German]
Bibliographic information 1978, Vol.26, No.1, p.7-21, and No.2, p.45-52. Illus. 160 ref.
Abstract The introduction mentions the environmental factors responsible for dermatitis, substances toxic to the skin, the types of exogenous toxic acne and criteria for differential diagnosis. The example of dioxin (2, 3, 7, 8-tetrachlorodibenzoparadioxin) shows the importance of minimal doses of highly toxic substances for medicine and dermatology (cases of dioxin contamination between 1949 and 1976 are enumerated). In view of its great toxicity, dioxin occupies a special place among acne-producing chloroaryls: toxic and teratogenic effects, manifestations of poisoning in man, dioxin acne. Detailed considerations are given on occupational contact acne due to chloroaryls: aetiology, clinical symptoms, history, pathogenesis, diagnosis, therapy, oil acne, tar acne, possibility of pseudoacne due to chlorine-free aromatic compounds. Part 2 deals with non-occupational contact acne.
Descriptors (primary) tetrachlorodibenzodioxin; dermal toxicity; chlorinated hydrocarbons; acne
Descriptors (secondary) oil acne; skin diseases; toxic substances; medical treatment; diagnosis; teratogenic effects; chloracne
Document type -
Subject(s) Occupational pathology
Broad subject area(s)
Browse category(ies) Heterocyclic compounds
Genetic factors in reaction to exposures
Skin diseases
Halogenated hydrocarbons